| Date | Location | Result | |
| 12/02/21 | Chicago, IL | Evansville 3, Sam Houston 0 (25-21,25-21,25-21) | Box score |
| 11/19/21 | Las Cruces, NM | Grand Canyon 3, Sam Houston 0 (25-20,25-21,25-17) | Box score |
| 11/18/21 | Las Cruces, NM | Sam Houston 3, Abilene Christian 0 (25-19,25-20,25-19) | Box score |
| 11/13/21 | Nacogdoches, TX | Sam Houston 3, Stephen F. Austin 1 (25-21,25-20,13-25,25-17) | Box score |
| 11/06/21 | Stephenville, TX | Sam Houston 3, Tarleton 2 (20-25,25-19,17-25,25-21,15-9) | Box score |
| 11/04/21 | Abilene, TX | Abilene Christian 3, Sam Houston 1 (15-25,25-21,25-20,25-21) | Box score |
| 10/30/21 | Huntsville, TX | Sam Houston 3, Lamar 0 (25-22,25-15,25-17) | Box score |
| 10/28/21 | Huntsville, TX | Sam Houston 3, UTRGV 1 (25-14,24-26,25-16,25-15) | Box score |
| 10/23/21 | Phoenix, AZ | Sam Houston 3, Utah Valley 0 (25-20,26-24,25-21) | Box score |
| 10/22/21 | Phoenix, AZ | Sam Houston 3, New Mexico State 1 (25-18,13-25,25-21,25-17) | Box score |
| 10/21/21 | Phoenix, AZ | Grand Canyon 3, Sam Houston 0 (31-29,25-16,25-16) | Box score |
| 10/16/21 | Edinburg, TX | UTRGV 3, Sam Houston 2 (25-16,21-25,25-21,27-29,15-12) | Box score |
| 10/14/21 | Beaumont, TX | Sam Houston 3, Lamar 0 (25-22,25-18,25-20) | Box score |
| 10/09/21 | Huntsville, TX | Sam Houston 3, Stephen F. Austin 0 (25-23,25-19,25-19) | Box score |
| 10/02/21 | Huntsville, TX | Sam Houston 3, Abilene Christian 0 (25-18,25-16,25-23) | Box score |
| 09/30/21 | Huntsville, TX | Sam Houston 3, Tarleton 1 (25-17,25-12,24-26,25-21) | Box score |
| 09/18/21 | Birmingham, AL | Texas Tech 3, Sam Houston 1 (25-17,22-25,25-20,28-26) | Box score |
| 09/17/21 | Birmingham, AL | UAB 3, Sam Houston 1 (25-23,23-25,25-18,25-23) | Box score |
| 09/17/21 | Birmingham, AL | Sam Houston 3, Tulane 2 (18-25,25-22,25-22,17-25,15-9) | Box score |
| 9/12/21 | Houston, Texas | Rice 3, Sam Houston 0 (25-21,28-26,25-17) | Box score |
| 9/11/21 | Houston, Texas | LSU 3, Sam Houston 1 (18-25,25-15,25-20,25-13) | Box score |
| 09/04/21 | Arlington, TX | Sam Houston 3, UT Arlington 2 (22-25,25-14,25-18,22-25,15-12) | Box score |
| 09/03/21 | Arlington, TX | North Texas 3, Sam Houston 2 (16-25,25-17,25-17,25-27,15-12) | Box score |
| 09/03/21 | Arlington, TX | Sam Houston 3, Tulsa 2 (25-14,24-26,23-25,25-16,15-8) | Box score |
| 08/28/21 | Huntsville, TX | Sam Houston 3, Houston Baptist 2 (27-25,17-25,26-24,28-30,15-12) | Box score |
| 08/28/21 | Huntsville, TX | Sam Houston 3, San Diego State 2 (25-23,13-25,14-25,25-15,15-9) | Box score |
| 08/27/21 | Huntsville, TX | Sam Houston 3, San Diego State 0 (25-18,25-18,25-20) | Box score |
| 08/27/21 | Huntsville, TX | Sam Houston 3, Houston Baptist 0 (25-17,26-24,25-22) | Box score |